Isaac Guerendo has shown potential as a running back with the San Francisco 49ers, proving to be a valuable asset when called upon last season. His performance, highlighted by a commendable average of 5.0 yards per carry, indicates his ability to capitalize on opportunities, especially during injury spells for the main roster players. As a backup to the star Christian McCaffrey, Guerendo's upside shines through, making him a player to monitor for fantasy leagues in 2025.

With McCaffrey's history of injuries, Guerendo could step into a larger role, offering fantasy managers an intriguing option should the need arise. His performance last season positions him as a potential starter, making him a worthy consideration in deeper leagues or as a handcuff in standard formats.

As fantasy football drafts approach, identifying emerging players can be crucial for success. Five second-year breakout candidates are making waves for the upcoming season: Malik Nabers, J.J. McCarthy, Drake Maye, Bucky Irving, and Isaac Guerendo. Each has shown flashes of brilliance, making them desirable targets for savvy fantasy managers. Nabers, despite his impressive rookie year, remains a potential sleeper. J.J. McCarthy, recovering from injury, offers high upside as he takes the helm for the Minnesota Vikings. Maye's rushing ability hints at a dual-threat future in New England, while Irving and Guerendo could solidify their roles in Tampa Bay and San Francisco, respectively.

As the NFL season approaches, savvy fantasy football players recognize the importance of securing backup running backs who can serve as handcuffs to starting players. Targeting players like Jordan Mason, Zach Charbonnet, Isaac Guerendo, Tank Bigsby, and Bhayshul Tuten can provide significant value, especially considering they often come at a discount during drafts. Players such as Jaylen Wright and others also emerge as prime candidates to stash on your bench.

Finding the right handcuff can mean the difference between winning and losing in fantasy leagues. Stashing these backups allows managers to cover injuries or unexpected performance dips from starters. Moreover, the strategy of identifying potential gems among backups fosters a proactive approach that is essential in today's competitive fantasy landscape.

Jordan James has shown effectiveness as a runner, particularly in gaining first downs and executing runs exceeding 10 yards, despite not consistently hitting the 100-yard mark. As a rookie for the San Francisco 49ers, he faces competition from Isaac Guerendo for the backup spot behind Christian McCaffrey, who has a history of injury that may open up opportunities for both players.

James has progressed from a backup at Oregon to a starter, albeit with some efficiency dips in his senior year. Training camp will be pivotal as James seeks to secure a solid role behind McCaffrey, whose health remains a concern given his past injuries. The coaching strategies under Kyle Shanahan further complicate the running back depth chart, yet they also provide a chance for James in a favorable offensive scheme.

As the NFL offseason progresses, the San Francisco 49ers face difficult decisions regarding their roster ahead of the upcoming season. One player whose future appears uncertain is second-year running back Isaac Guerendo, recently mentioned as a potential trade candidate. The addition of rookies Jordan James and Corey Kiner has raised eyebrows regarding Guerendo's position on the team.

Guerendo's previous season showcased his dual threat as a runner and a pass catcher, evidenced by his impressive catch rate. However, his tendency to hesitate at times has drawn criticism, making his spot in the pecking order less secure. Should he find a way to improve his decisiveness, he could solidify his role in what is a competitive backfield alongside established star Christian McCaffrey. The 49ers' willingness to trade him hinges on the performances of their new rookies and their overall confidence in Guerendo's development.