The San Francisco 49ers are set to commence their training camp on July 22, 2025, as they prepare for the upcoming season. With a total roster of 90 players, the team faces the challenge of trimming down to the final 53 ahead of their season opener against the Seattle Seahawks on September 7. The camp is crucial this year as numerous spots on the depth chart remain unsettled, providing a golden opportunity for many players to secure their place. Rookies will be vying for essential roles as they look to make their mark amidst competition for limited spots.

Quarterback Brock Purdy, alongside Mac Jones and Tanner Mordecai, will lead the offensive line-up while Christian McCaffrey anchors the running back position. The wide receiver group features notable players such as Brandon Aiyuk and Russell Gage Jr., aiming to elevate the team's passing game. Defensively, the roster is headlined by stalwarts like Nick Bosa and Fred Warner, while depth across the line and in the secondary will be tested throughout the camp. The 49ers are meticulously reviewing player performances, ready to make necessary adjustments based on injuries and the overall effectiveness of their squad.