Kyle Juszczyk enters concussion protocol and won’t play the 49ers’ home opener vs. Arizona, thinning a core blocking and passing-game role.

Jauan Jennings is day-to-day with shoulder and ankle injuries, likely limited or out Week 3.

Bartch is out with a high-ankle sprain, pushing rookie Connor Colby into left guard and hinting at a longer-term role if he keeps it up.

The Saints game saw 21 personnel fall to 13.2%, signaling a faster, more versatile attack against a Cardinals secondary led by Will Johnson.