McCaffrey’s Week 1 workload was 31 touches, and Week 2 injury chatter centered on a calf scare. He practiced fully late in the week and wasn’t listed on the Sunday injury report, making him a strong play against New Orleans unless a late setback arises.

The 49ers’ backfield remains in flux. If McCaffrey can’t go, Brian Robinson would step into the top role and Isaac Guerendo could mix in behind him. Shanahan offered little new detail beyond saying there was nothing to report after Week 1, keeping fantasy managers on alert for last‑minute lineup decisions.