Brock Purdy’s turf-toe injury sidelines the 49ers QB for up to five weeks, thrusting Mac Jones into Sunday’s matchup with New Orleans. Fantasy managers should scan the QB streamer list, with Daniel Jones, Trevor Lawrence, and even Aaron Rodgers cited as viable options in tougher spots.

Week 1’s injury avalanche continued with Austin Ekeler’s season-ending Achilles and George Kittle’s hamstring. Add in Xavier Worthy’s shoulder and Brock Bowers’s knee, and the waiver wire becomes a chessboard. Watch for sleepers like Harold Fannin Jr. and Emeka Egbuka to emerge for deeper leagues.