Christian McCaffrey’s calf issue clouds San Francisco’s Week 1 plan against Seattle. Limited practice hints at a potential workload dip, pushing fantasy managers to consider contingency options and depth plays early in the season.

If McCaffrey is limited, Jordan Mason and the 49ers’ crew could absorb extra touches, while SF’s passing game and screen work may pick up the slack. Seattle faces a test if McCaffrey is more limited than expected, elevating the value of SF’s pass-catching options and backup runners in early-season lineups.