Purdy headlines an elite SF offense when healthy, backed by McCaffrey, Kittle and Aiyuk with Pearsall flashing as a late-peaking option. The line to monitor is Purdy’s 3,850 passing yards, a mark that seems reasonable given volume and schedule if weapons stay healthy. The 49ers’ defense is younger up front, creating upside and risk in similar measure; Mykel Williams’ rookie impact could swing run-defense moments, but health and depth remain the decisive wildcards for fantasy outcomes.