Jennings returns to 49ers practice as game week arrives, with a fresh window to prove himself for an extension and a path to big early-season production if he stays healthy. Bourne’s visit adds a veteran wrinkle to SF’s depth chart, while Gage’s return keeps Week 1 WR plans fluid and could tilt target shares in Seattle. Purdy and Kittle anchor the offense, Moody’s lingering kicking questions loom, and the defense faces a Seahawks test that will expose SF’s plan for the run game and pass rush. The looming Bosa contract and Shanahan’s game management remain central to fantasy angles as SF aims to navigate health, division games, and a volatile Week 1 environment.

Mike McDonald and Seattle’s new-look scheme add complexity for SF’s approach, with Sam Darnold facing a blitz-heavy plan and SF’s young players expected to contribute early. In this landscape, Jennings’ Week 1 trajectory hinges on health and volume, while Purdy’s supporting cast—Kittle and McCaffrey—must carry pace. Sleeper’s nudges aside, the opener serves as a proving ground for how SF balances youth and vets over a 17-game horizon, especially given the division’s early tests.