Brock Purdy could return to practice in a limited capacity ahead of Week 3 after a toe injury, raising optimism for a possible Week 3 return or emergency third QB setup vs Arizona. Eight 49ers missed practice, including Kyle Juszczyk and Siran Neal with concussions and key vets like Trent Williams, Nick Bosa, and Christian McCaffrey on rest days or limited designations. The latest timeline hints Purdy could be back sooner than feared, with a two-week recovery being plausible.

Fantasy angle: Purdy’s return would reshape San Francisco’s aerial ceiling, while McCaffrey’s workload is a key watch given the injury designations. Jennings and Williams are trending to play, but neck-and-neck with health; Juszczyk/Neal concussion protocols add depth risk. Week 3 game plan against Arizona looms large for SF’s offense and fantasy upside.