George Kittle lands on injured reserve with a hamstring in a tight 49ers schedule storm, four games in 23 days. Earliest return could be Oct. 12 at Tampa Bay if a four-week window holds. Jake Moody is waived after a misfire and a blocked kick as Eddy Pineiro visits for a potential replacement. With Kittle out, Luke Farrell and Jake Tonges step in at tight end, Kyle Juszczyk may see more inline TE duties, and Brayden Willis could be elevated from the practice squad if needed.

Moody’s shaky SF tenure and Pineiro’s visit add kicking uncertainty beyond Robbie Gould’s legacy. The Niners must navigate a grueling stretch against New Orleans, Arizona, Jacksonville and the Rams, while Purdy looks to sustain timing with a reshaped TE corps. Fantasy implications center on reduced Kittle volume early and how SF redistributes targets and red-zone chances during this heavy slate.