San Francisco stands at an inflection point in 2025, leaning on a rising core as the window on glorious runs tightens. Purdy carries the weight of a five-year, $265 million deal and must elevate a new supporting cast to keep the offense humming. Bosa remains elite, but a younger line around him requires more dominance to keep the defense rolling. Pearsall needs a breakout year as the No. 1 option, while Shanahan’s job security adds a pressure layer on every decision.

As the 49ers navigate this crossroads, fantasy managers should watch Purdy’s development, Pearsall’s opportunity window, and the defense’s ability to adapt with rookies ready to contribute. The blend of veteran expectations and a growing young backbone signals a potential regroup-and-rise season rather than a simple continuation of the ascent.