SF travels to New Orleans with Brock Purdy sidelined by a turf toe-like injury, handing Mac Jones his first start for the 49ers. The game plan leans on Christian McCaffrey as the focal point, both on the ground and in the receiving game, while the defense tries to bottle up the Saints’ rushing attack. Ricky Pearsall emerges as a bigger aerial option with Jennings banged up, and San Francisco must execute a clean game to steal Week 2 on the road.